Biocomputing Hub Publications

Publications

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Work in progress

We are currently adding the publications corresponding to Hub projects.

 

Mechanism of homology search expansion during recombinational DNA break repair in Saccharomyces cerevisiae

Team Piazza
Team Jost
Laurent Modolo
https://doi.org/10.1016/j.molcel.2024.08.003
Jan 1, 2024
Agnès Dumont, Nicolas Mendiboure, Jérôme Savocco, Loqmen Anani, Pierrick Moreau, Agnès Thierry, Laurent Modolo, Daniel Jost, Aurèle Piazza

 

Mechanism of homology search expansion during recombinational DNA break repair in Saccharomyces cerevisiae

Team SBDM
Laurent Modolo
https://doi.org/10.1186/s12915-024-01846-9
Jan 1, 2024
Camille Fourneaux, Laëtitia Racine, Catherine Koering, Sébastien Dussurgey, Elodie Vallin, Alice Moussy, Romuald Parmentier, Fanny Brunard, Daniel Stockholm, Laurent Modolo, Franck Picard, Olivier Gandrillon, Andras Paldi, Sandrine Gonin-Giraud

 

Kernel-based testing for single-cell differential analysis

Team SBDM
Ghislain Durif
https://doi.org/10.1186/s13059-024-03255-1
Jan 1, 2024
Ozier-Lafontaine, A., Fourneaux, C., Durif, G., Arsenteva, P., Vallot, C., Gandrillon, O., Gonin-Giraud, S., Michel, B., Picard, F.

 

Translation-dependent and -independent mRNA decay occur through mutually exclusive pathways defined by ribosome density during T cell activation

Team RMI2
Team Regards
Nicolas Fontrodona
Laurent Modolo
https://doi.org/10.1101/gr.277863.123
Jan 1, 2024
Blandine C. Mercier, Emmanuel Labaronne, David Cluet, Laura Guiguettaz, Nicolas Fontrodona, Alicia Bicknell, Antoine Corbin, Mélanie Wencker, Fabien Aube, Laurent Modolo, Karina Jouravleva, Didier Auboeuf, Melissa J. Moore, Emiliano P. Ricci

 

Condensin positioning at telomeres by shelterin proteins drives sister-telomere disjunction in anaphase

Team Bernard
Laurent Modolo
https://doi.org/10.7554/eLife.89812.3
Jan 1, 2023
Léonard Colin, Celine Reyes, Julien Berthezene, Laetitia Maestroni, Laurent Modolo, Esther Toselli, Nicolas Chanard, Stephane Schaak, Olivier Cuvier, Yannick Gachet, Stephane Coulon, Pascal Bernard, Sylvie Tournier

 

SplicingLore: a web resource for studying the regulation of cassette exons by human splicing factors

Team Regards
Stéphane Janczarski
https://doi.org/10.1093/database/baad091
Jan 1, 2023
Polvèche Hélène, Valat Jessica, Fontrodona Nicolas, Lapendry Audrey, Clerc Valentine, Janczarski Stéphane, Mortreux Franck, Auboeuf Didier, Bourgeois Cyril F

 

Characterizing the interplay between gene nucleotide composition bias and splicing

Team Regards
Laurent Modolo
https://doi.org/10.1186/s13059-019-1869-y
Jan 1, 2022
Sébastien Lemaire, Nicolas Fontrodona, Fabien Aubé, Jean-Baptiste Claude, Hélène Polvèche, Laurent Modolo, Cyril F. Bourgeois, Franck Mortreux, Didier Auboeuf

 

RNA helicase-dependent gene looping impacts messenger RNA processing

Team Regards
Team Bernard
Laurent Modolo
https://doi.org/10.1093/nar/gkac717
Jan 1, 2022
Sophie Terrone, Jessica Valat, Nicolas Fontrodona, Guillaume Giraud, Jean-Baptiste Claude, Emmanuel Combe, Audrey Lapendry, Hélèene Polvèche, Lamya Ben Ameur, Arnaud Duvermy, Laurent Modolo, Pascal Bernard, Franck Mortreux, Didier Auboeuf, Cyril F. Bourgeois

 

Evidence for close molecular proximity between reverting and undifferentiated cells

Team SBDM
Laurent Modolo
https://doi.org/10.1186/s12915-022-01363-7
Jan 1, 2022
Souad Zreika, Camille Fourneaux, Elodie Vallin, Laurent Modolo, Rémi Seraphin, Alice Moussy, Elias Ventre, Matteo Bouvier, Anthony Ozier-Lafontaine, Arnaud Bonnaffoux, Franck Picard, Olivier Gandrillon, Sandrine Gonin-Giraud

 

Spen modulates lipid droplet content in adult Drosophila glial cells and protects against paraquat toxicity

Team Mollereau
David Cluet
https://doi.org/10.1038/s41598-020-76891-9
Jan 1, 2020
Victor Girard, Valérie Goubard, Matthieu Querenet, Laurent Seugnet, Laurent Pays, Serge Nataf, Eloïse Dufourd, David Cluet, Bertrand Mollereau, Nathalie Davoust

 

Males as somatic investment in a parthenogenetic nematode

Team Delattre
Laurent Modolo
https://doi.org/10.1126/science.aau0099
Jan 1, 2019
Manon Grosmaire, Caroline Launay, Marion Siegwald, Thibault Brugière, Lilia Estrada-Virrueta, Duncan Berger, Claire Burny, Laurent Modolo, Mark Blaxter, Peter Meister, Marie-Anne Félix, Pierre-Henri Gouyon, Marie Delattre

 

Interplay between coding and exonic splicing regulatory sequences

Team Regards
Laurent Modolo
https://doi.org/10.1101/gr.241315.118
Jan 1, 2019
Nicolas Fontrodona, Fabien Aubé, Jean-Baptiste Claude, Hélène Polvèche, Sébastien Lemaire, Léon-Charles Tranchevent, Laurent Modolo, Franck Mortreux, Cyril F Bourgeois, Didier Auboeuf

 

Condensin controls cellular RNA levels through the accurate segregation of chromosomes instead of directly regulating transcription

Team Bernard
Laurent Modolo
https://doi.org/10.1126/science.aau0099
Jan 1, 2018
Clémence Hocquet, Xavier Robellet, Laurent Modolo, Xi-Ming Sun, Claire Burny, Sara Cuylen-Haering, Esther Toselli, Sandra Clauder-Münster, Lars Steinmetz, Christian H Haering, Samuel Marguerat, Pascal Bernard
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